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KMID : 0371320030650060572
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Journal of the Korean Surgical Society
2003 Volume.65 No. 6 p.572 ~ p.575
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Hyalinizing Trabecular Adenoma of Thyroid
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Park Kyoung-Sik
Kim Seok-Won
Min Hye-Sook
Han Won-Shik
Roh Dong-Young
Park Seong-Hoe
Youn Yeo-Kyu
Oh Seung-Keun
Choi Kook-Jin
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Abstract
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The Hyalinizing trabecular adenoma oi the thyroid is a uncommon benign neoplasm which is characterized by trabecular growth pattern with hyaline stroma of the basal membrane type. It is often misdiagnosed as papillary carcinoma due to its peculiar cytologic and histologic features such as, nuclear grooving and papillary structures, or as medullary carcinoma due to the hyalinized stroma resembling amyroid. Special stains and immunohistochemical studies are required to make a definite diagnosis. A 34-year old woman was admitted suffering from a left neck mass. Computed tomography showed a 2 cm-sized mass in the left thyroid. Fine needle aspiration cytology suggested papillary carcinoma. Intraoperative frozen section suggested medullary carcinoma and H&E staining suggested medullary carcinoma. However according to immunohistochemistry which revealed calc tonin negative, the tumor was reviewed and finally diagnosed as hyaline trabecular adenoma. The hyalinizing trabecular adenoma, although uncommon, is certainly worth consideration in order to avoid being misinterpreted as carcinoma on the basis of individual cytologic and histologic features.
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KEYWORD
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